Robert T Dirksen Selected Research

Acetylcysteine (Siran)

9/2015

Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death.

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Robert T Dirksen Research Topics

Disease

24	Malignant Hyperthermia 11/2022 - 10/2004
16	Central Core Myopathy (Central Core Disease) 06/2021 - 07/2002
11	Muscular Diseases (Myopathy) 10/2023 - 07/2002
9	Myotonic Dystrophy (Dystrophia Myotonica) 10/2016 - 08/2005
6	Contracture 01/2022 - 02/2006
5	Muscle Weakness 01/2023 - 07/2002
5	Rhabdomyolysis 06/2021 - 06/2009
4	Sudden Death 09/2015 - 06/2009
3	Muscular Dystrophies (Muscular Dystrophy) 06/2021 - 11/2008
3	Paralysis (Palsy) 11/2020 - 03/2010
3	Fatigue 10/2017 - 01/2013
3	Heart Failure 01/2014 - 07/2003
3	Myotonia 12/2010 - 01/2007
2	Neoplasms (Cancer) 12/2022 - 11/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2022 - 11/2008
2	Heat Stress Disorders (Heat Cramp) 01/2022 - 11/2014
2	Congenital Structural Myopathies (Centronuclear Myopathy) 11/2018 - 09/2013
2	Long QT Syndrome 01/2018 - 10/2016
2	Polymorphic catecholergic ventricular tachycardia 01/2017 - 08/2006
2	Inborn Genetic Diseases (Disease, Hereditary) 10/2016 - 03/2012
2	Body Weight (Weight, Body) 09/2015 - 01/2013
2	Minicore Myopathy with External Ophthalmoplegia 03/2010 - 10/2004
2	Hypoxia (Hypoxemia) 11/2008 - 07/2008
2	Channelopathies 12/2007 - 04/2007
2	Cardiomyopathies (Cardiomyopathy) 08/2006 - 07/2003
1	Liver Failure 02/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2022
1	Alzheimer Disease (Alzheimer's Disease) 03/2022
1	Inflammation (Inflammations) 01/2022
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022
1	Bone Resorption 01/2022
1	Metabolic Bone Diseases (Osteopenia) 01/2022
1	Arthritis (Polyarthritis) 01/2022
1	Synovitis 01/2022
1	Sarcopenia 06/2021
1	Atrophic Muscular Disorders 06/2021
1	Multiple pterygium syndrome 11/2020
1	Distal Myopathies (Distal Muscular Dystrophy) 11/2020
1	Myalgia 11/2020
1	King Denborough syndrome 11/2020
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2020
1	Muscular Atrophy (Muscle Atrophy) 01/2019
1	Crush Injuries 01/2019
1	Hypertrophy 10/2018
1	Ventricular Remodeling 10/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Native American myopathy 10/2017
1	Huntington Disease (Huntington's Disease) 01/2017
1	Seizures (Absence Seizure) 10/2016
1	Pain (Aches) 01/2016
1	Atrophy 09/2015
1	Fibrosis (Cirrhosis) 07/2014

Drug/Important Bio-Agent (IBA)

36	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 01/2023 - 07/2002
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2004
6	CalciumIBA 11/2020 - 02/2006
5	Anesthetics (Anesthetic Agents)IBA 01/2022 - 02/2006
4	Caffeine (No Doz)FDA LinkGeneric 01/2022 - 02/2006
4	Halothane (Fluothane)FDA Link 01/2022 - 02/2006
3	RNA (Ribonucleic Acid)IBA 01/2017 - 12/2005
3	Messenger RNA (mRNA)IBA 01/2007 - 08/2005
2	Adenosine Monophosphate (AMP)IBA 11/2022 - 01/2021
2	DystrophinIBA 01/2022 - 07/2014
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2016
2	IonsIBA 10/2017 - 12/2007
2	Myotonin-Protein KinaseIBA 10/2016 - 01/2007
2	Carrier Proteins (Binding Protein)IBA 09/2015 - 07/2009
2	Superoxides (Superoxide)IBA 11/2008 - 07/2008
2	Chloride Channels (Chloride Channel)IBA 12/2007 - 01/2007
2	ChloridesIBA 12/2007 - 04/2007
2	Protein Isoforms (Isoforms)IBA 01/2007 - 07/2002
1	EnzymesIBA 02/2023
1	Triglycerides (Triacylglycerol)IBA 02/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2022
1	IronIBA 03/2022
1	NitrogenIBA 06/2021
1	Oxygen (Dioxygen)IBA 06/2021
1	4-Aminopyridine (4 Aminopyridine)FDA Link 01/2019
1	Potassium Channel Blockers (Blockers, Potassium Channel)IBA 01/2019
1	Tamoxifen FDA LinkGeneric 11/2018
1	Transcription Factors (Transcription Factor)IBA 10/2018
1	myocardinIBA 10/2018
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	Cysteine (L-Cysteine)FDA Link 10/2017
1	Cyclic NucleotidesIBA 10/2016
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	Purinergic Receptors (Receptors, Purine)IBA 01/2016
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 09/2015
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 09/2015
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 09/2015
1	Acetylcysteine (Siran)FDA LinkGeneric 09/2015
1	AcidsIBA 09/2015
1	AntioxidantsIBA 09/2015
1	Drinking WaterIBA 09/2015
1	Creatine Kinase (Creatine Phosphokinase)IBA 07/2014
1	Sarcoglycans (beta Sarcoglycan)IBA 07/2014

Therapy/Procedure

5	Therapeutics 10/2023 - 10/2016
2	Anesthesia 11/2014 - 02/2006
1	Radiotherapy 12/2022
1	Intraperitoneal Injections 09/2015
1	Ligation 01/2015